Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21165781 | 0.73 | TSHR (0.52) | TSHRNPSR1KDM4EXBP1HPGD | |
| SCHEMBL4455809 | 0.66 | ALDH1A1 (0.59) | TSHRHPGDRAB9ANPC1MEN1 | |
| SCHEMBL29121393 | 0.65 | NPC1 (0.71) | NPSR1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28664345 | 0.64 | SMO (0.55) | KDM4ENPC1MEN1KMT2AGSK3B | |
| SCHEMBL18528796 | 0.64 | NPC1 (0.69) | NPSR1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4157253 | 0.64 | PTPN2 (0.68) | KDM4EHPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4931668 | 0.63 | TSHR (0.59) | TSHRNPSR1KDM4EXBP1HPGD | |
| SCHEMBL13679017 | 0.63 | PTPN1 (0.53) | NPSR1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL15288798 | 0.62 | L3MBTL1 (0.51) | NPSR1KDM4EXBP1RAB9ASMN1; SMN2 | |
| SCHEMBL27820679 | 0.62 | TSHR (0.59) | TSHRNPSR1KDM4EXBP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019139365-A1 | NOVEL PHENYLSULFONYL OXAZOLE DERIVATIVE AND USE THEREOF | 경북대학교 산학협력단 | 2019-07-18 | — | — | WO | disclosed |