SCHEMBL21165786

SCHEMBL21165786

COC(=O)c1ccc(Oc2ccc(C(C)C)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
MAPT P10636 5/20 0.53
RAB9A P51151 6/20 0.51
NPC1 O15118 2/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
PRSS1 P07477 1/20 0.50
ACR P10323 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA12 O43570 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
STS P08842 1/20 0.49
KDM4E B2RXH2 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL84424 0.91 CA1 (0.59) CA1CA2MAPTRAB9ANPC1
SCHEMBL69218 0.87 CA1 (0.75) CA1CA2MAPTRAB9AMEN1
SCHEMBL2627834 0.85 CA1 (0.56) CA1CA2MAPTRAB9ANPC1
SCHEMBL26117767 0.84 CA1 (0.56) CA1CA2MAPTRAB9AMEN1
SCHEMBL22666461 0.83 ACR (0.59) CA1CA2MAPTRAB9ANPC1
SCHEMBL25819341 0.83 ACACB (0.54) MAPTRAB9ANPC1MEN1KMT2A
SCHEMBL194410 0.83 ACACB (0.54) MAPTRAB9ANPC1MEN1KMT2A
SCHEMBL28266239 0.82 CDC25A (0.54) CA1CA2MAPTRAB9ANPC1
SCHEMBL21656686 0.82 LMNA (0.59) ALDH1A1SMN1; SMN2KDM4EL3MBTL1
SCHEMBL4242980 0.81 PARP10 (0.63) CA1CA2MAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed
US-20190219938-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC CARTRIDGE AND IMAGE FORMING APPARATUS INCLUDING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK CA1 4881/4885CA2 4416/4885MAPT 2272/4885
US-11591289-B2 Aromatic compounds AHR, TYR, MUSK CA1 4882/4885CA2 4221/4885MAPT 2195/4885
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK CA1 4881/4885CA2 4416/4885MAPT 2272/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR CA1 3602/4885CA2 1477/4885MAPT 4404/4885
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK CA1 4881/4885CA2 4416/4885MAPT 2272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.