Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 7/20 | 0.35 |
| ▸ | DRD3 | P35462 | 6/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.35 |
| ▸ | CDK2 | P24941 | 5/20 | 0.35 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22475837 | 0.84 | MAP4K3 (0.49) | METMAP4K3PDPK1 | |
| SCHEMBL22475838 | 0.72 | GPR84 (0.35) | GPR84DRD4DRD3DRD2CDK2 | |
| SCHEMBL22475864 | 0.70 | GPR84 (0.43) | GPR84CDK2METCYP3A4CYP2C19 | |
| SCHEMBL21167798 | 0.70 | FGFR1 (0.54) | DRD4DRD3CDK2CYP3A4CYP2C19 | |
| SCHEMBL22475696 | 0.69 | MET (0.44) | GPR84CCNE1CDK2METCYP3A4 | |
| SCHEMBL21167357 | 0.67 | MET (0.47) | METMAP4K3PDPK1 | |
| SCHEMBL21167697 | 0.67 | MTNR1A (0.44) | GPR84CYP3A4CYP2C19PDPK1 | |
| SCHEMBL23127946 | 0.66 | BCHE (0.34) | GPR84DRD4DRD3DRD2MET | |
| SCHEMBL2197248 | 0.64 | GPR84 (0.50) | GPR84DRD4DRD3DRD2CCNE1 | |
| SCHEMBL24591031 | 0.64 | MET (0.61) | GPR84CCNE1CDK2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |