Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 7/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.39 |
| ▸ | CCR4 | P51679 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16234979 | 0.78 | CRHBP (0.41) | ALDH1A1GAAHPGDSMN1; SMN2CRHBP | |
| SCHEMBL29364510 | 0.78 | CRHBP (0.41) | ALDH1A1GAAHPGDSMN1; SMN2CRHBP | |
| SCHEMBL1191752 | 0.77 | APP (0.35) | ALDH1A1PDCD1LG2CD274CCR4MEN1 | |
| SCHEMBL19407671 | 0.77 | CRHBP (0.59) | ALDH1A1GAAHPGDSMN1; SMN2CRHBP | |
| SCHEMBL30503540 | 0.77 | CRHBP (0.59) | ALDH1A1GAAHPGDSMN1; SMN2CRHBP | |
| SCHEMBL15195554 | 0.76 | CRHBP (0.42) | ALDH1A1GAAHPGDSMN1; SMN2CRHBP | |
| SCHEMBL2614478 | 0.76 | APOBEC3A (0.40) | ALDH1A1HPGDSMN1; SMN2PDCD1LG2CD274 | |
| SCHEMBL19002845 | 0.75 | CRHBP (0.38) | ALDH1A1GAAHPGDSMN1; SMN2CRHBP | |
| SCHEMBL25246695 | 0.74 | PDCD1LG2 (0.40) | PDCD1LG2CD274 | |
| SCHEMBL17477974 | 0.74 | CRHBP (0.41) | ALDH1A1GAAHPGDSMN1; SMN2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371352-A | Synthesis method of 6-chloro-3-fluoro-2-methoxypyridine | 上海毕臣生化科技有限公司 | 2025-01-28 | — | — | CN | claimed |
| EP-4735430-A1 | MALT1 INHIBITORS | Janssen Pharmaceutica NV (BE) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025076285-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | DELPHIA THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| CN-119613320-A | Synthesis method of compound 3-iodo-1H-indole-2-carboxylic acid | 上海毕臣生化科技有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119371352-A | Synthesis method of 6-chloro-3-fluoro-2-methoxypyridine | 上海毕臣生化科技有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-119371352-A | Synthesis method of 6-chloro-3-fluoro-2-methoxypyridine | 上海毕臣生化科技有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-119371352-A | Synthesis method of 6-chloro-3-fluoro-2-methoxypyridine | 上海毕臣生化科技有限公司 | 2025-01-28 | — | — | CN | disclosed |
| WO-2025003414-A1 | MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-02 | — | — | WO | disclosed |
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | SCHRÖDINGER, INC. | 2024-01-25 | — | — | US | disclosed |
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |
| EP-2626350-A1 | CYCLOPROPANE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2013-08-14 | — | — | EP | disclosed |
| EP-2626350-A1 | CYCLOPROPANE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-8268848-B2 | Cyclopropane compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-09-18 | — | — | US | disclosed |
| US-8268848-B2 | Cyclopropane compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20120095031-A1 | CYCLOPROPANE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20120095031-A1 | CYCLOPROPANE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095031-A1 | CYCLOPROPANE COMPOUND | HCRTR1, HCRTR2, CNR1 | ALDH1A1 2708/4885GAA 4462/4885HPGD 2630/4885 |
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | PDXK, HIPK1, PCK1 | ALDH1A1 4740/4885GAA 905/4885HPGD 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.