Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.37 |
| ▸ | PTGES | O14684 | 4/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17811611 | 0.92 | PTGES (0.35) | ESR1ESR2GSTP1ALOX5PTGES | |
| SCHEMBL14972789 | 0.90 | ESR1 (0.36) | ESR1ESR2GSTP1ALOX5PTGES | |
| SCHEMBL23449826 | 0.90 | GSTP1 (0.46) | ESR1ESR2GSTP1ALOX5PTGES | |
| SCHEMBL27520183 | 0.90 | PSMB5 (0.35) | GSTP1ALOX5PTGESHSD17B1HSD17B2 | |
| SCHEMBL24638595 | 0.89 | GSTP1 (0.42) | ESR1ESR2GSTP1ALOX5PTGES | |
| SCHEMBL25580307 | 0.89 | HSD17B1 (0.36) | ESR1ESR2GSTP1ALOX5PTGES | |
| SCHEMBL25580304 | 0.89 | HSD17B1 (0.36) | ESR1ESR2GSTP1ALOX5PTGES | |
| SCHEMBL20313374 | 0.89 | ESR1 (0.44) | ESR1ESR2GSTP1ALOX5PTGES | |
| SCHEMBL19089871 | 0.89 | ESR1 (0.44) | ESR1ESR2GSTP1ALOX5PTGES | |
| SCHEMBL25000699 | 0.88 | MEN1 (0.37) | ESR1ESR2GSTP1ALOX5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231534-A1 | ARYLDIAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-07-23 | — | — | US | disclosed |
| EP-3511316-A1 | ARYLDIAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2019-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231534-A1 | ARYLDIAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | FTO, SLC19A1, ALKBH1 | ESR1 477/4885ESR2 463/4885GSTP1 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.