SCHEMBL21169810

SCHEMBL21169810

Cc1ccc(N(c2ccccc2)c2ccc3c4cc5c(cc4n4c6ccccc6c2c34)c2ccc(N(c3ccccc3)c3ccc(Cc4cccc(N(c6cccc(C)c6)c6ccc7c8cc9c(cc8n8c%10ccccc%10c6c78)c6ccc(N(c7ccccc7)c7cccc(C)c7)c7c8ccccc8n9c67)c4)cc3)c3c4ccccc4n5c23)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21169706 0.94 SIGMAR1 (0.30) —
SCHEMBL27013426 0.90 MAPT (0.32) MEN1KMT2ANPSR1ALDH1A1MAPT
SCHEMBL20857989 0.88 MAPT (0.33) MEN1KMT2ANPSR1ALDH1A1MAPT
SCHEMBL20857830 0.86 SRC (0.32) MEN1KMT2ANPSR1MAPTTP53
SCHEMBL24718899 0.86 — —
SCHEMBL27128200 0.85 TP53 (0.30) TP53
SCHEMBL27013427 0.84 SIGMAR1 (0.36) MEN1KMT2AMAPTTP53
SCHEMBL20857826 0.84 TP53 (0.32) MEN1KMT2ANPSR1ALDH1A1MAPT
SCHEMBL22382150 0.84 HTR6 (0.30) MAPT
SCHEMBL23109654 0.83 FLT3 (0.30) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-27 — — US disclosed
US-20230011996-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2023-01-12 — — US disclosed
US-11552259-B1 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 — — US disclosed
US-20190221747-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L MEN1 1048/4885KMT2A 3104/4885NPSR1 4495/4885
US-20230011996-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME RER1, RPS19, ESR1 MEN1 1901/4885KMT2A 2030/4885NPSR1 2854/4885
US-20190221747-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND KCNN4, OR10J3, KCNN2 MEN1 688/4885KMT2A 2435/4885NPSR1 3063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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