Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 2/20 | 0.40 |
| ▸ | USP7 | Q93009 | 2/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21173223 | 0.94 | S100A4 (0.43) | USP8USP7S100A4MAPTPKM | |
| SCHEMBL21173224 | 0.84 | LCK (0.36) | MAPTPKMALDH1A1GAAMEN1 | |
| SCHEMBL25656471 | 0.84 | LCK (0.36) | MAPTPKMALDH1A1GAAMEN1 | |
| SCHEMBL21173226 | 0.83 | MAPT (0.39) | USP8USP7MAPTPKMALDH1A1 | |
| SCHEMBL21173229 | 0.83 | PKM (0.39) | MAPTPKMALDH1A1GAAMEN1 | |
| SCHEMBL2681526 | 0.80 | S100A4 (0.42) | USP8USP7S100A4MAPTPKM | |
| SCHEMBL2681524 | 0.80 | S100A4 (0.42) | USP8USP7S100A4MAPTPKM | |
| SCHEMBL16977316 | 0.80 | S100A4 (0.42) | USP8USP7S100A4MAPTPKM | |
| SCHEMBL25747895 | 0.80 | ALDH1A1 (0.33) | MAPTPKMALDH1A1GAAEGFR | |
| SCHEMBL21851277 | 0.79 | USP8 (0.36) | USP8USP7S100A4MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019137354-A1 | THIOPHENE-BASED FUSED AROMATIC SYSTEMS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-07-18 | — | — | WO | disclosed |