SCHEMBL6013

SCHEMBL6013

O=C(Cl)COc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.68
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
ALPL P05186 1/20 0.53
ALPI P09923 1/20 0.53
ALPG P10696 1/20 0.53
HPGD P15428 1/20 0.52
NPC1 O15118 3/20 0.51
RAB9A P51151 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
FFAR1 O14842 1/20 0.50
GAA P10253 1/20 0.50
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
PTPN7 P35236 1/20 0.48
PTPN12 Q05209 1/20 0.48
PKM P14618 1/20 0.48
LMNA P02545 1/20 0.47
ALOX5 P09917 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27943650 0.98 ALOX15 (0.65) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL8729465 0.94 ALOX15 (0.61) ALOX15KMT2AMEN1ALPLALPI
Pyridine SCHEMBL2046976 0.89 LMNA (0.55) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL2117441 0.88 ALOX15 (0.50) ALOX15KMT2AMEN1HPGDSMN1; SMN2
SCHEMBL2324869 0.88 MAPT (0.58) ALOX15KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL3054083 0.85 PLA2G4B (0.64) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL27943877 0.85 GAA (0.62) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL4362709 0.84 LMNA (0.56) ALOX15KMT2AMEN1GAAALDH1A1
SCHEMBL10760471 0.84 USP2 (0.50) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL10760470 0.84 USP2 (0.50) ALOX15KMT2AMEN1ALPLALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2257 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118874671-A Enhanced flotation desilication technology for high-silicon magnesite 辽宁科技学院 2024-11-01 CN claimed
CN-118496175-A TRADD inhibitor derivative and preparation method and application thereof 安徽医科大学 2024-08-16 CN claimed
CN-117986232-A Oxime ester photoinitiator, preparation method and application thereof 常州强力电子新材料股份有限公司 2024-05-07 CN claimed
CN-117924393-A Monomer of 3' -mercapto nucleoside analogue and its synthesis process 天津兴博润生物制药有限公司 2024-04-26 CN claimed
CN-116199617-A Oxime ester compound, preparation method thereof and photo-curing composition 常州强力电子新材料股份有限公司 2023-06-02 CN claimed
CN-116199616-A Modified oxime ester compound, preparation method thereof and photo-curing composition 常州强力电子新材料股份有限公司 2023-06-02 CN claimed
CN-115970908-A Application method of 2-decadione and phenoxyl acetyl chloride in reverse flotation desilication and decalcification of magnesite 福州大学 2023-04-18 CN claimed
CN-109705794-B Low-viscosity UV/moisture dual-curing polyurethane hot melt adhesive and preparation method thereof 重庆中科力泰高分子材料股份有限公司 2022-10-04 CN claimed
CN-113462346-B UV/moisture dual-curing polyurethane hot melt adhesive with high initial adhesion and excellent drop resistance, and preparation method and application thereof 重庆中科力泰高分子材料股份有限公司 2022-07-22 CN claimed
CN-113462346-A UV/moisture dual-curing polyurethane hot melt adhesive with high initial adhesion and excellent drop resistance, and preparation method and application thereof 重庆中科力泰高分子材料股份有限公司 2021-10-01 CN claimed
EP-0688775-A1 Method for the purification of 23 -E isomers of 23-imino derivatives of LL-F28249 compounds American Cyanamid Company (US) 1995-12-27 EP claimed
US-5478951-A Method for the purification of 23-E isomers of 23-imino derivatives of LL-F28249 compounds AMERICAN CYANAMID COMPANY (US) 1995-12-26 US claimed
EP-0586570-A1 BACKBONE MODIFIED OLIGONUCLEOTIDE ANALOGUES ISIS PHARMACEUTICALS, INC. (US) 1994-03-16 EP claimed
US-5254681-A Process for preparing monobactames and their intermediate product CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1993-10-19 US claimed
WO-1992020822-A1 BACKBONE MODIFIED OLIGONUCLEOTIDE ANALOGUES ISIS PHARMACEUTICALS, INC. (US) 1992-11-26 WO claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
EP-0411541-A2 Process for preparing monobactames and their intermediate product CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1991-02-06 EP claimed
EP-0090203-B1 PROCESS FOR PREPARING P.CHLOROPHENOXYACETYL-PIPERONYLPIPERAZINE RAVIZZA S.p.A. (IT) 1986-11-12 EP claimed
US-4025580-A ACYLATION IN PRESENCE OF LEWIS ACID CATALYST; BIODEGRADABLE PACKAGING OWENS-ILLINOIS, INC. (US) 1977-05-24 US claimed
US-4006059-A Hydrophobic noncovalent binding of proteins to support materials PURDUE RESEARCH FOUNDATION (US) 1977-02-01 US claimed