Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 6/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119022 | 0.88 | PSEN1 (0.46) | CYP2C9KMT2ALMNAC5AR1ALDH1A1 | |
| SCHEMBL2118388 | 0.88 | LMNA (0.41) | HSD17B1HSD17B2CYP2C9KMT2ALMNA | |
| SCHEMBL2117311 | 0.80 | HSD17B1 (0.43) | HSD17B1HSD17B2CYP2C9KMT2ANPC1 | |
| SCHEMBL2119838 | 0.78 | HSD17B1 (0.44) | HSD17B1HSD17B2CYP2C9KMT2ANPC1 | |
| SCHEMBL2118381 | 0.75 | HSD17B1 (0.43) | HSD17B1HSD17B2CYP2C9NPC1RAB9A | |
| SCHEMBL2119868 | 0.74 | POLB (0.46) | HSD17B2CYP2C9RAB9ALMNAGAA | |
| SCHEMBL2119577 | 0.69 | MAPT (0.54) | CYP2C9KMT2ANPC1LMNAC5AR1 | |
| SCHEMBL2117866 | 0.68 | TAAR1 (0.47) | HSD17B1HSD17B2CYP2C9KMT2ALMNA | |
| SCHEMBL2118249 | 0.68 | PSEN1 (0.45) | CYP2C9KMT2ALMNAC5AR1ALDH1A1 | |
| SCHEMBL20036778 | 0.67 | ERN1 (0.53) | HSD17B1HSD17B2LMNAERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | HSD17B1 3178/4885HSD17B2 3651/4885CYP2C9 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.