Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2122135 | 0.88 | LMNA (0.41) | CYP2C9C5AR1CA12CA1CA2 | |
| SCHEMBL2120607 | 0.88 | PSEN1 (0.45) | CYP2C9C5AR1CA12CA1CA2 | |
| SCHEMBL2118160 | 0.81 | CYP2E1 (0.45) | CYP2C9RAB9AKAT6AGHSRLMNA | |
| SCHEMBL2119838 | 0.80 | HSD17B1 (0.44) | HSD17B1HSD17B2CYP2C9C5AR1NPC1 | |
| SCHEMBL2117311 | 0.76 | HSD17B1 (0.43) | HSD17B1HSD17B2CYP2C9C5AR1NPC1 | |
| SCHEMBL2119380 | 0.76 | LMNA (0.39) | CYP2C9NPC1RAB9ALMNAHDAC3 | |
| SCHEMBL2119048 | 0.75 | GHSR (0.58) | HSD17B1HSD17B2CYP2C9CA12CA1 | |
| SCHEMBL2117632 | 0.75 | HSD17B1 (0.44) | HSD17B1HSD17B2CYP2C9C5AR1NPC1 | |
| SCHEMBL7053207 | 0.74 | KDM4E (0.50) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL1062982 | 0.71 | LTA4H (0.57) | CYP2C9NPC1ERN1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | HSD17B1 3178/4885HSD17B2 3651/4885CYP2C9 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.