Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.32 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.32 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.32 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177912 | 1.00 | PLAAT3 (0.32) | PLAAT3PLAAT5PLAAT2PLAAT4TRPA1 | |
| SCHEMBL21178060 | 0.89 | MAOB (0.39) | — | |
| SCHEMBL21177721 | 0.85 | TDP1 (0.35) | PLAAT3PLAAT5PLAAT2PLAAT4KMT2A | |
| SCHEMBL21177725 | 0.82 | ALDH1A1 (0.40) | NFE2L2KDM4EALDH1A1KMT2A | |
| SCHEMBL21177858 | 0.82 | ALDH1A1 (0.40) | NFE2L2KDM4EALDH1A1KMT2A | |
| SCHEMBL21177855 | 0.81 | LTA4H (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4TRPA1 | |
| SCHEMBL21177845 | 0.81 | MAOB (0.45) | NFE2L2CYP1A2CYP2C19KMT2A | |
| SCHEMBL21182299 | 0.81 | MAOB (0.45) | NFE2L2CYP1A2CYP2C19KMT2A | |
| SCHEMBL21177849 | 0.78 | SIGMAR1 (0.37) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 | |
| SCHEMBL21177883 | 0.78 | SIGMAR1 (0.37) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143143-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROBLASTOMA OR RHEUMATOID ARTHRITIS | 숙명여자대학교 산학협력단 | 2019-07-25 | — | — | WO | disclosed |
| WO-2019143142-A1 | NOVEL PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING GLIOBLASTOMA | 숙명여자대학교 산학협력단 | 2019-07-25 | — | — | WO | disclosed |