Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27912703 | 0.84 | MAPT (0.39) | ELOVL1PTGS2PTGS1SLC34A1ALDH1A1 | |
| SCHEMBL21177704 | 0.72 | KMO (0.38) | ELOVL1SLC34A1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21177942 | 0.71 | CYP1A2 (0.36) | ELOVL1ALDH1A1KDM4EMAPTCYP1A2 | |
| SCHEMBL31199040 | 0.70 | CRACR2A (0.42) | — | |
| SCHEMBL537516 | 0.70 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL21177290 | 0.70 | CYP1A2 (0.36) | ELOVL1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL537523 | 0.68 | TGFBR1 (0.44) | PTGS2PTGS1ALDH1A1KDM4EMEN1 | |
| SCHEMBL31199137 | 0.67 | CRACR2A (0.38) | PTGS2PTGS1ALDH1A1KDM4EMEN1 | |
| SCHEMBL21177620 | 0.67 | CYP1A2 (0.38) | ELOVL1ALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL31199062 | 0.67 | MAPT (0.44) | ALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141957-A1 | N-PYRIMIDINYL HYDROXY PYRAZOLE DERIVATIVES AND USES THEREOF | CADO BIOTECHNOLOGY IVS (DK) | 2019-07-25 | — | — | WO | disclosed |