Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 5/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179381 | 0.72 | ELOVL1 (0.32) | ELOVL1SLC34A1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21177942 | 0.68 | CYP1A2 (0.36) | ELOVL1HCRTR1HCRTR2KDM5AKDM4C | |
| SCHEMBL21177290 | 0.65 | CYP1A2 (0.36) | ELOVL1HCRTR1HCRTR2ALDH1A1CYP1A2 | |
| SCHEMBL21177924 | 0.63 | NPSR1 (0.48) | SLC34A1ALDH1A1HSD17B10NPSR1GRM5 | |
| SCHEMBL31053654 | 0.63 | ALDH1A1 (0.45) | GRIN2BALDH1A1HSD17B10GRM5ALOX15 | |
| SCHEMBL21177620 | 0.62 | CYP1A2 (0.38) | ELOVL1HCRTR1HCRTR2ALDH1A1CYP1A2 | |
| SCHEMBL17895403 | 0.61 | PTGER1 (0.58) | ALDH1A1 | |
| SCHEMBL12003474 | 0.61 | GRM5 (0.44) | KMOKDM5AKDM4CKDM5BALDH1A1 | |
| SCHEMBL14277965 | 0.60 | KEAP1 (0.53) | KMOCA1CA2CYP11B1CYP11B2 | |
| SCHEMBL29413795 | 0.60 | NPC1 (0.48) | ALDH1A1CYP1A2CYP3A4CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141957-A1 | N-PYRIMIDINYL HYDROXY PYRAZOLE DERIVATIVES AND USES THEREOF | CADO BIOTECHNOLOGY IVS (DK) | 2019-07-25 | — | — | WO | disclosed |