Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21180023 | 0.81 | ERN1 (0.44) | ALDH1A1POLBSMN1; SMN2FYNCYP1A2 | |
| SCHEMBL19759545 | 0.81 | AAK1 (0.48) | ALDH1A1POLBSMN1; SMN2CYP17A1FYN | |
| SCHEMBL21095840 | 0.79 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2FYNCYP1A2 | |
| SCHEMBL15340842 | 0.79 | HDAC4 (0.46) | ALDH1A1POLBSMN1; SMN2CYP1A2CYP2E1 | |
| SCHEMBL10272836 | 0.78 | IMPDH2 (0.55) | ALDH1A1CYP17A1CYP1A2CYP2E1CYP2D6 | |
| SCHEMBL11994404 | 0.74 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2FYNCYP1A2 | |
| SCHEMBL27316386 | 0.74 | SMN1; SMN2 (0.51) | ALDH1A1POLBSMN1; SMN2FYN | |
| SCHEMBL29246430 | 0.73 | SLC22A12 (0.46) | ALDH1A1POLBSMN1; SMN2CYP1A2CYP2E1 | |
| SCHEMBL30421671 | 0.73 | SLC22A12 (0.46) | ALDH1A1POLBSMN1; SMN2CYP1A2CYP2E1 | |
| SCHEMBL2036717 | 0.73 | CA12 (0.54) | ALDH1A1CYP17A1SLC22A12CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10781171-B2 | Substituted pyrrolidines as G-protein coupled receptor 43 agonists | EPICS THERAPEUTICS (BE) | 2020-09-22 | — | — | US | disclosed |
| US-10358416-B2 | Substituted pyrrolidines as G-protein coupled receptor 43 agonists | EPICS THERAPEUTICS (BE) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10781171-B2 | Substituted pyrrolidines as G-protein coupled receptor 43 agonists | GPR119, GPR52, GPR88 | ALDH1A1 1244/4885POLB 3627/4885SMN1; SMN2 4049/4885 |
| US-10358416-B2 | Substituted pyrrolidines as G-protein coupled receptor 43 agonists | GIPR, GPR88, GPR119 | ALDH1A1 1453/4885POLB 2460/4885SMN1; SMN2 3980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.