Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134201 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL69496 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL374026 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL373936 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL28116182 | 0.77 | ALOX15 (0.38) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL27916979 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| SCHEMBL374081 | 0.74 | OPRM1 (0.41) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL20109282 | 0.73 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL13545112 | 0.73 | SMN1; SMN2 (0.41) | ALDH1A1LMNAHSD17B10POLBOPRM1 | |
| SCHEMBL15797775 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10358417-B2 | Method for preparing efficiently synthetic sitafloxacin intermediate (7S)-5-azaspiro[2.4]heptane-7-yl tert-butyl carbamate | CHEN-STONE (GUANGZHOU) CO., LTD. (CN) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10358417-B2 | Method for preparing efficiently synthetic sitafloxacin intermediate (7S)-5-azaspiro[2.4]heptane-7-yl tert-butyl carbamate | TYMS, CYP51A1, TPMT | ALDH1A1 2182/4885LMNA 4437/4885HSD17B10 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.