Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176235 | 0.84 | ALOX15 (0.48) | CYP2D6CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL374740 | 0.83 | GABRP (0.56) | CYP2D6CYP2C19ALDH1A1LMNANOD1 | |
| SCHEMBL7286437 | 0.83 | GABRP (0.56) | CYP2D6CYP2C19ALDH1A1LMNANOD1 | |
| SCHEMBL1538912 | 0.83 | ALOX15 (0.54) | CYP2D6CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL573710 | 0.83 | L3MBTL1 (0.53) | CYP2D6CYP2C9CYP2C19ALDH1A1HSD17B10 | |
| SCHEMBL207116 | 0.83 | L3MBTL1 (0.53) | CYP2D6CYP2C9CYP2C19ALDH1A1HSD17B10 | |
| SCHEMBL4948196 | 0.83 | GABRP (0.56) | CYP2D6CYP2C19ALDH1A1LMNANOD1 | |
| SCHEMBL374738 | 0.83 | L3MBTL1 (0.53) | CYP2D6CYP2C9CYP2C19ALDH1A1HSD17B10 | |
| SCHEMBL1538915 | 0.83 | ALOX15 (0.54) | CYP2D6CYP2C9CYP2C19ALDH1A1LMNA | |
| Acetic Acid SCHEMBL28340742 | 0.82 | L3MBTL1 (0.49) | CYP2D6CYP2C9CYP2C19ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206787-A1 | PRODRUGS OF GLUTAMINE ANALOGS | Ústav organické chemie a biochemie AV CR, v.v.i. (CZ) | 2021-07-08 | — | — | US | disclosed |
| EP-3514158-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | Aptinyx Inc. (US) | 2019-07-24 | — | — | EP | disclosed |
| CN-103946220-B | Inhibitors of baculovirus containing fragment {2- [4- (biphenyl-4-yl) -1H-imidazol-2-yl ] pyrrolidine-1-carbonylmethyl } amine | 施万生物制药研发IP有限责任公司 | 2017-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206787-A1 | PRODRUGS OF GLUTAMINE ANALOGS | GLUL, GLS, GLS2 | CYP2D6 104/4885CYP2C9 227/4885CYP2C19 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.