Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623559 | 0.76 | CRBN (0.39) | CRBNDDB1PKM | |
| SCHEMBL103923 | 0.71 | LMNA (0.36) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL27879438 | 0.67 | CDK1 (0.41) | CRBN | |
| SCHEMBL4426345 | 0.67 | XDH (0.54) | CYP3A4BLMLMNA | |
| SCHEMBL79000 | 0.67 | XDH (0.51) | CYP3A4BLMLMNA | |
| SCHEMBL8712615 | 0.67 | L3MBTL1 (0.33) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL28277546 | 0.66 | CRBN (0.48) | CRBNDDB1DUTLMNAPKM | |
| SCHEMBL25378286 | 0.65 | — | — | |
| SCHEMBL11894064 | 0.65 | — | — | |
| SCHEMBL22016090 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38090-E1 | Antitumor activity; useful for treatment and prevention of cancers | Matsuda, Akira (JP) | 2003-04-22 | — | — | US | claimed |