Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28426470 | 0.79 | CRBN (0.58) | CRBNDDB1ALDH1A1L3MBTL1DUT | |
| SCHEMBL9109048 | 0.67 | TRIM24 (0.50) | ATMTRIM24TRIM33ALDH1A1CYP1A2 | |
| SCHEMBL30773547 | 0.64 | CRBN (0.47) | CRBNDDB1POLBGAADUT | |
| SCHEMBL11623275 | 0.64 | CRBN (0.42) | CRBNDDB1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL1396218 | 0.64 | TRIM24 (0.42) | ATMTRIM24TRIM33ALDH1A1CYP1A2 | |
| SCHEMBL2561871 | 0.63 | CRBN (0.50) | CRBNDDB1ALDH1A1L3MBTL1DUT | |
| SCHEMBL6227943 | 0.63 | CRBN (0.41) | CRBNDDB1ALDH1A1POLBGAA | |
| SCHEMBL21183289 | 0.63 | CRBN (0.45) | CRBNDDB1ALDH1A1L3MBTL1DUT | |
| SCHEMBL10423652 | 0.62 | — | — | |
| SCHEMBL7157402 | 0.62 | CRBN (0.44) | CRBNDDB1DUTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |