SCHEMBL21184237

SCHEMBL21184237

CO[C@@H]1[C@H](O)[C@@H](COP(=O)(OC)OP(=O)(OC)OP(=O)(OC)OC)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 1/20 0.61
▸ TGM2 P21980 1/20 0.59
▸ TAS1R3 Q7RTX0 2/20 0.58
▸ TAS1R1 Q7RTX1 2/20 0.58
▸ FUT5 Q11128 1/20 0.55
▸ HINT1 P49773 3/20 0.55
▸ KRAS P01116 9/20 0.54
▸ IMPDH2 P12268 2/20 0.54
▸ IMPDH1 P20839 1/20 0.54
▸ DCPS Q96C86 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18271828 0.93 TGM2 (0.61) NT5ETGM2TAS1R3TAS1R1FUT5
SCHEMBL21184238 0.93 NT5E (0.71) NT5ETGM2TAS1R3TAS1R1FUT5
SCHEMBL25391360 0.89 TAS1R3 (0.70) NT5ETGM2TAS1R3TAS1R1FUT5
SCHEMBL720437 0.89 TAS1R3 (0.70) NT5ETGM2TAS1R3TAS1R1FUT5
SCHEMBL14576179 0.89 TAS1R3 (0.70) NT5ETGM2TAS1R3TAS1R1FUT5
SCHEMBL600378 0.89 TAS1R3 (0.70) NT5ETGM2TAS1R3TAS1R1FUT5
SCHEMBL26067681 0.89 TAS1R3 (0.70) NT5ETGM2TAS1R3TAS1R1FUT5
SCHEMBL21184323 0.89 TGM2 (0.68) NT5ETGM2TAS1R3TAS1R1FUT5
SCHEMBL19325472 0.89 TGM2 (0.68) NT5ETGM2TAS1R3TAS1R1FUT5
SCHEMBL18763616 0.89 TGM2 (0.68) NT5ETGM2TAS1R3TAS1R1FUT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190225644-A1 MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING MODERNATX, INC. 2019-07-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225644-A1 MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING RNGTT, RNMT, NSUN2 NT5E 572/4885TGM2 3563/4885TAS1R3 4195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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