Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213117 | 0.94 | MAPK14 (0.32) | MAPK14NPC1NTRK1 | |
| SCHEMBL2726246 | 0.87 | NTRK1 (0.33) | MAPK14NPC1NTRK1 | |
| SCHEMBL213271 | 0.86 | SCD5 (0.34) | NPC1 | |
| SCHEMBL212791 | 0.86 | MAPT (0.40) | NPC1 | |
| SCHEMBL211534 | 0.82 | CSNK2A2 (0.40) | NPC1 | |
| SCHEMBL212349 | 0.82 | MAPT (0.34) | NPC1 | |
| SCHEMBL213118 | 0.81 | FOLH1 (0.34) | MAPK14NPC1NTRK1 | |
| SCHEMBL211687 | 0.81 | MAPT (0.40) | NTRK1 | |
| SCHEMBL210927 | 0.81 | KDM4E (0.37) | NPC1 | |
| SCHEMBL210463 | 0.81 | MAPT (0.41) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |