Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186199 | 0.86 | NPC1 (0.59) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL21186198 | 0.83 | NPC1 (0.49) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL21186155 | 0.75 | MAPT (0.53) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL21186002 | 0.74 | KMT2A (0.64) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL21186205 | 0.73 | SCD (0.64) | NPC1RAB9AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL21186162 | 0.72 | MAPT (0.48) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL21186147 | 0.71 | NPC1 (0.55) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL21186172 | 0.71 | NPC1 (0.55) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL21186178 | 0.69 | RAB9A (0.72) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL21186171 | 0.69 | NPC1 (0.62) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |