Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966295 | 0.84 | TDP1 (0.59) | ALDH1A1TDP1KDM4EMAPTMEN1 | |
| SCHEMBL1275295 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1KDM4EMAPTMEN1 | |
| SCHEMBL28858385 | 0.73 | PABPC1 (0.50) | ALDH1A1TDP1KDM4EMAPTTSHR | |
| SCHEMBL22562123 | 0.72 | CDC25B (0.50) | ALDH1A1TDP1CTSDKDM4EMAPT | |
| SCHEMBL6929649 | 0.70 | CDC25B (0.50) | ALDH1A1TDP1KDM4EMAPTMEN1 | |
| SCHEMBL14048634 | 0.68 | RAB9A (0.57) | ALDH1A1TDP1KDM4EMAPTMEN1 | |
| SCHEMBL7915013 | 0.67 | ALDH1A1 (0.67) | ALDH1A1TDP1CTSDKDM4EMAPT | |
| SCHEMBL11775136 | 0.66 | ALDH1A1 (0.42) | ALDH1A1TDP1KDM4EMAPTMEN1 | |
| SCHEMBL21468310 | 0.66 | MEN1 (0.63) | ALDH1A1TDP1KDM4EMAPTMEN1 | |
| SCHEMBL28976146 | 0.66 | ALDH1A1 (0.53) | ALDH1A1TDP1CTSDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034839-B2 | Compounds, linked with haptens, for the detection of senescent cells | THE UNIVERSITY OF MANCHESTER (GB) | 2021-06-15 | — | — | US | disclosed |
| US-20190225812-A1 | COMPOUNDS, LINKED WITH HAPTENS, FOR THE DETECTION OF SENESCENT CELLS | THE UNIVERSITY OF MANCHESTER (GB) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225812-A1 | COMPOUNDS, LINKED WITH HAPTENS, FOR THE DETECTION OF SENESCENT CELLS | CCNB1, LMNB1, S100B | ALDH1A1 906/4885TDP1 1104/4885CTSD 2753/4885 |
| US-11034839-B2 | Compounds, linked with haptens, for the detection of senescent cells | CCNB1, LMNB1, S100B | ALDH1A1 906/4885TDP1 1104/4885CTSD 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.