Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 7/20 | 0.56 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21340749 | 0.87 | MAOB (0.56) | RAB9AMAOBADAMTS4MMP2MMP13 | |
| SCHEMBL4339666 | 0.83 | MAOB (0.61) | RAB9AMAOBL3MBTL1GAAMAPT | |
| SCHEMBL11562469 | 0.83 | NR4A2 (0.63) | NR4A2KMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL4638512 | 0.83 | MAOB (0.50) | RAB9AMAOBADAMTS4MMP2MMP13 | |
| SCHEMBL17514658 | 0.81 | RAB9A (0.53) | RAB9AMAOBADAMTS4MMP2MMP13 | |
| SCHEMBL2983086 | 0.80 | MAOB (0.50) | RAB9AMAOBNR4A2INPPL1MAOA | |
| SCHEMBL26128621 | 0.80 | DHFR (0.44) | RAB9AADAMTS4MMP2MMP13MMP14 | |
| SCHEMBL13220843 | 0.80 | RAB9A (0.53) | RAB9AMAOBADAMTS4MMP2MMP13 | |
| SCHEMBL29955554 | 0.80 | RAB9A (0.53) | RAB9AMAOBADAMTS4MMP2MMP13 | |
| SCHEMBL1283762 | 0.80 | CACNA1C (0.59) | RAB9AMAOBL3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730850-B | Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline | 山东百启生物医药有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-116730850-A | Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline | 山东百启生物医药有限公司 | 2023-09-12 | — | — | CN | claimed |
| EP-4676926-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| US-20250214976-A1 | GPR35 MODULATORS AND USES THEREOF | CROSSIGNAL THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
| CN-116730850-B | Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline | 山东百启生物医药有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-116730850-B | Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline | 山东百启生物医药有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-116730850-B | Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline | 山东百启生物医药有限公司 | 2025-05-27 | — | — | CN | disclosed |
| EP-4504712-A1 | GPR35 MODULATORS AND USES THEREOF | Crossignal Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| CN-119137105-A | GPR35 modulators and uses thereof | 交信医药研发公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2024184650-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS. | ThirtyFiveBio Limited (GB) | 2024-09-12 | — | — | WO | disclosed |
| WO-2023196538-A1 | GPR35 MODULATORS AND USES THEREOF | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| CN-116730850-A | Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline | 山东百启生物医药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116730850-A | Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline | 山东百启生物医药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116730850-A | Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline | 山东百启生物医药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |
| CN-1930121-A | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER PROD INC (US) | 2007-03-14 | — | — | CN | disclosed |
| US-20060258723-A1 | Substituted Heteroaryl- and Phenylsulfamoyl Compounds | PFIZER INC | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258723-A1 | Substituted Heteroaryl- and Phenylsulfamoyl Compounds | PPARG, PPARA, PPARD | RAB9A 2063/4885MAOB 4396/4885ADAMTS4 4353/4885 |
| US-20250214976-A1 | GPR35 MODULATORS AND USES THEREOF | GPR35, GPR34, GPR68 | RAB9A 4154/4885MAOB 3706/4885ADAMTS4 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.