Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.31 |
| ▸ | PCNA | P12004 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroquinone SCHEMBL9403963 | 0.91 | ALDH1A1 (0.40) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7736947 | 0.83 | ALOX15 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| Bisphenol A SCHEMBL8740866 | 0.81 | ESR1 (0.50) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL5765450 | 0.81 | ENPP2 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8740886 | 0.80 | GAA (0.42) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL15093765 | 0.76 | MEN1 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL674989 | 0.76 | TNK2 (0.40) | ALDH1A1KMT2AMEN1KDM4C | |
| SCHEMBL15093959 | 0.76 | MEN1 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL222919 | 0.76 | MEN1 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10323707 | 0.75 | ICAM1 (0.42) | ALDH1A1KMT2AMEN1APPKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158652-B2 | 1-Difluoromethyl-5-{4-[3-(1-piperidinyl)propoxy]phenyl}-2(1H)-pyridone; compounds act as histamine-H3 receptor antagonistic substances or inverse-agonistic substances; useful as preventives or remedies for various circular system diseases, nervous system diseases, metabolic system diseases | MSD K.K. (JP) | 2012-04-17 | — | — | US | disclosed |
| US-7811467-B2 | Optical film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-12 | — | — | US | disclosed |
| US-20080269287-A1 | Substituted Pyridone Derivative | MSD K.K. (JP) | 2008-10-30 | — | — | US | disclosed |
| US-20070298191-A1 | Optical Film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-12-27 | — | — | US | disclosed |
| EP-1820797-A1 | SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269287-A1 | Substituted Pyridone Derivative | HRH3, HRH4, HRH1 | CA12 4851/4885CA1 4369/4885CA2 3661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.