SCHEMBL21186322

SCHEMBL21186322

c1cc(-c2ccc3oc4nc5c6ccccc6c6ccccc6c5nc4c3c2)cc(-c2cc3ccccc3c3ccccc23)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.40
PLA2G2A P14555 4/20 0.37
PLA2G4A P47712 4/20 0.37
PLA2G10 O15496 1/20 0.37
PIM1 P11309 1/20 0.35
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
PIM3 Q86V86 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
ALDH1A1 P00352 5/20 0.34
HPGD P15428 4/20 0.34
MAPT P10636 3/20 0.34
KDM4E B2RXH2 3/20 0.34
TSHR P16473 2/20 0.34
CASP1 P29466 2/20 0.34
HSD17B10 Q99714 2/20 0.34
ALOX15 P16050 1/20 0.34
CASP7 P55210 1/20 0.34
TBK1 Q9UHD2 1/20 0.34
KMT2A Q03164 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19887516 0.90 CYP11B1 (0.40) CYP11B1PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL21185963 0.90 CA12 (0.38) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2
SCHEMBL21176409 0.88 PLA2G2A (0.41) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2
SCHEMBL30929927 0.88 PLA2G2A (0.41) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2
SCHEMBL19887630 0.88 CYP11B1 (0.38) CYP11B1PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL21185964 0.88 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2
SCHEMBL21185965 0.87 HSD17B1 (0.39) CYP11B1PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL25013610 0.84 ALOX5 (0.50) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2
SCHEMBL30929925 0.84 ALOX5 (0.50) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2
SCHEMBL21176406 0.84 ALOX5 (0.50) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230027613-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-01-26 US disclosed
US-20190229278-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027613-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device NFE2L2, AOX1, CCNE2 CYP11B1 1757/4885PLA2G2A 3209/4885PLA2G4A 3403/4885
US-20190229278-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device NFE2L2, AOX1, CCNE2 CYP11B1 1757/4885PLA2G2A 3209/4885PLA2G4A 3403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.