Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187148 | 0.87 | MAOA (0.45) | EPHX2NPC1RAB9AEPHX1KMT2A | |
| SCHEMBL21187213 | 0.87 | NPC1 (0.48) | EPHX2NPC1RAB9AEPHX1MAPK14 | |
| SCHEMBL21187183 | 0.79 | RAB9A (0.46) | NPC1RAB9AL3MBTL1POLBMAPT | |
| SCHEMBL21187143 | 0.79 | RAB9A (0.46) | NPC1RAB9AL3MBTL1POLBMAPT | |
| SCHEMBL21187151 | 0.78 | EPHX2 (0.42) | EPHX2NPC1RAB9AEPHX1KMT2A | |
| SCHEMBL21187136 | 0.76 | SMN1; SMN2 (0.40) | EPHX2L3MBTL1KMT2APOLBMAPT | |
| SCHEMBL21187095 | 0.76 | KMT2A (0.41) | TRPV1KMT2APOLBMEN1DPP4 | |
| SCHEMBL21187130 | 0.76 | SMN1; SMN2 (0.39) | EPHX2L3MBTL1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21177092 | 0.72 | NPC1 (0.45) | EPHX2NPC1RAB9AEPHX1L3MBTL1 | |
| SCHEMBL21177091 | 0.72 | NPC1 (0.45) | EPHX2NPC1RAB9AEPHX1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141095-A1 | AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |