Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 9/20 | 0.37 |
| ▸ | FPR2 | P25090 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187130 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2FPR1FPR2KMT2AMEN1 | |
| SCHEMBL21187146 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2FPR1FPR2KMT2AMEN1 | |
| SCHEMBL21187220 | 0.81 | FPR2 (0.38) | FPR1FPR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL21187148 | 0.78 | MAOA (0.45) | SMN1; SMN2FPR1FPR2KMT2AALDH1A1 | |
| SCHEMBL21187193 | 0.78 | THRB (0.38) | SMN1; SMN2ALDH1A1EPHX2THRB | |
| SCHEMBL21187127 | 0.78 | THRB (0.38) | SMN1; SMN2ALDH1A1EPHX2THRB | |
| SCHEMBL21187123 | 0.78 | THRB (0.38) | SMN1; SMN2ALDH1A1EPHX2THRB | |
| SCHEMBL21187155 | 0.77 | KMT2A (0.37) | SMN1; SMN2KMT2AMEN1ALDH1A1EPHX2 | |
| SCHEMBL21187135 | 0.76 | EPHX2 (0.40) | SMN1; SMN2KMT2AMEN1EPHX2L3MBTL1 | |
| SCHEMBL17258589 | 0.73 | QDPR (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141095-A1 | AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |