Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187148 | 0.86 | MAOA (0.45) | EPHX2EPHX1NPC1RAB9AKMT2A | |
| SCHEMBL21187213 | 0.85 | NPC1 (0.48) | EPHX2EPHX1NPC1RAB9AGRIN2B | |
| SCHEMBL21187220 | 0.84 | FPR2 (0.38) | EPHX2EPHX1MEN1KMT2AMAPT | |
| SCHEMBL21187135 | 0.78 | EPHX2 (0.40) | EPHX2EPHX1NPC1RAB9AMEN1 | |
| SCHEMBL11525429 | 0.77 | KDM1A (0.49) | CCR6 | |
| SCHEMBL11525435 | 0.77 | KDM1A (0.49) | CCR6 | |
| SCHEMBL17737374 | 0.74 | EPHX2 (0.61) | EPHX2NPC1RAB9AGRIN2BKCNA5 | |
| SCHEMBL20838758 | 0.74 | EPHX2 (0.61) | EPHX2NPC1RAB9AGRIN2BKCNA5 | |
| SCHEMBL21187183 | 0.74 | RAB9A (0.46) | NPC1RAB9AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL21187143 | 0.74 | RAB9A (0.46) | NPC1RAB9AMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141095-A1 | AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |