Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.36 |
| ▸ | EPOR | P19235 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21189149 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1LTA4HSLC7A5 | |
| SCHEMBL21189273 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1LTA4HSLC7A5 | |
| SCHEMBL57869 | 0.85 | KYNU (0.46) | ALDH1A1ELANEPRTN3 | |
| SCHEMBL21189146 | 0.85 | KYNU (0.46) | ALDH1A1ELANEPRTN3 | |
| SCHEMBL21189177 | 0.85 | KYNU (0.46) | ALDH1A1ELANEPRTN3 | |
| SCHEMBL21189144 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1LTA4HKMT2A | |
| SCHEMBL21189194 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1LTA4HKMT2A | |
| SCHEMBL57868 | 0.82 | L3MBTL1 (0.37) | ALDH1A1MAPK1L3MBTL1ELANEPRTN3 | |
| SCHEMBL21189140 | 0.81 | SLC7A5 (0.44) | SLC7A5BTN3A1SLC1A5 | |
| SCHEMBL21189139 | 0.81 | SLC7A5 (0.44) | SLC7A5BTN3A1SLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774098-B2 | Nahlsgen optical resolution method | KYOTO UNIVERSITY (JP) | 2020-09-15 | — | — | US | disclosed |
| US-20190225634-A1 | NAHLSGEN OPTICAL RESOLUTION METHOD | KYOTO UNIVERSITY (JP) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10774098-B2 | Nahlsgen optical resolution method | HACL2, HAO2, HPD | ALDH1A1 150/4885MAPK1 486/4885L3MBTL1 1313/4885 |
| US-20190225634-A1 | NAHLSGEN OPTICAL RESOLUTION METHOD | HACL2, HAO2, HPD | ALDH1A1 150/4885MAPK1 486/4885L3MBTL1 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.