SCHEMBL21189676

SCHEMBL21189676

CC(c1ccc(C2CCCCC2)cc1)(c1cc(-c2ccc(S)cc2)ccc1S)c1cc(-c2ccc(S)cc2)ccc1S

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
MAPT P10636 2/20 0.35
HSP90AA1 P07900 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NOTUM Q6P988 2/20 0.33
P2RY14 Q15391 4/20 0.32
DGAT1 O75907 1/20 0.32
SIGMAR1 Q99720 3/20 0.32
ADRB3 P13945 2/20 0.31
TMEM97 Q5BJF2 2/20 0.31
HTR1B P28222 1/20 0.31
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31
APP P05067 1/20 0.31
CNR2 P34972 2/20 0.31
GALR1 P47211 1/20 0.31
ACE P12821 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22737898 0.95 CYP3A4 (0.38) CYP3A4CYP2C9MAPTHSP90AA1GAA
SCHEMBL21189637 0.83 KIF11 (0.31)
SCHEMBL21189812 0.83 KIF11 (0.31)
SCHEMBL21189421 0.82 CYP3A4 (0.41) CYP3A4CYP2C9MAPTHSP90AA1GAA
SCHEMBL21189420 0.81 CYP3A4 (0.38) CYP3A4CYP2C9MAPTHSP90AA1GAA
SCHEMBL23861380 0.80 CYP3A4 (0.43) CYP3A4CYP2C9MAPTHSP90AA1GAA
SCHEMBL22737900 0.79 CYP3A4 (0.34) CYP3A4CYP2C9
SCHEMBL21189414 0.78 KIF11 (0.40) CYP3A4CYP2C9MAPTCNR2ACE
SCHEMBL21189631 0.78 KIF11 (0.40) CYP2C9
SCHEMBL22738049 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019142897-A1 COMPOUND, RESIN, COMPOSITION, AND PATTERN FORMING METHOD 三菱瓦斯化学株式会社 2019-07-25 WO disclosed