SCHEMBL21201558

SCHEMBL21201558

CSCC(N)C(=O)NC(C)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 9/20 0.39
METAP1 P53582 6/20 0.39
DPP4 P27487 6/20 0.39
DPP8 Q6V1X1 5/20 0.39
DPP9 Q86TI2 5/20 0.39
ERAP2 Q6P179 1/20 0.33
ERAP1 Q9NZ08 1/20 0.33
LNPEP Q9UIQ6 1/20 0.33
DPP7 Q9UHL4 3/20 0.32
TSHR P16473 1/20 0.31
SLC15A1 P46059 1/20 0.31
MME P08473 1/20 0.31
ACE P12821 1/20 0.31
CPA1 P15085 1/20 0.31
ACE2 Q9BYF1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26425835 0.85 METAP2 (0.48) METAP2METAP1DPP4DPP8DPP9
SCHEMBL24915215 0.83 DPP4 (0.39) METAP2METAP1DPP4DPP8DPP9
SCHEMBL30788713 0.82 DPP4 (0.40) DPP4DPP8DPP9ERAP2ERAP1
SCHEMBL19502439 0.82 DPP4 (0.46) METAP2METAP1DPP4DPP8DPP9
SCHEMBL16421587 0.80 OPRD1 (0.38) METAP2METAP1DPP4DPP8DPP9
SCHEMBL7313525 0.80 SLC7A5 (0.48) DPP4DPP8DPP9ERAP2ERAP1
SCHEMBL30799694 0.80 DPP4 (0.42) DPP4DPP8DPP9ERAP2ERAP1
SCHEMBL26869128 0.80 PTGS1 (0.41) DPP4DPP8DPP9ERAP2ERAP1
SCHEMBL19934725 0.80 PTGS1 (0.41) DPP4DPP8DPP9ERAP2ERAP1
SCHEMBL31447508 0.80 DPP4 (0.42) DPP4DPP8DPP9ERAP2ERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10365290-B2 Multifunctional protein molecular weight ladders LI-COR, INC. (US) 2019-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10365290-B2 Multifunctional protein molecular weight ladders MPEG1, PSMB11, ACP1 METAP2 253/4885METAP1 49/4885DPP4 3557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.