Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224389 | 0.83 | HSP90AA1 (0.62) | HSP90AA1RXFP1MGAMGAASI | |
| SCHEMBL25209653 | 0.82 | MGAM (0.51) | HSP90AA1RXFP1MGAMGAASI | |
| SCHEMBL8816840 | 0.81 | HSP90AA1 (0.51) | HSP90AA1MAPTMEN1KMT2AKDM4E | |
| Bromide SCHEMBL8817521 | 0.80 | HSP90AA1 (0.50) | HSP90AA1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30729451 | 0.76 | ALDH1A1 (0.51) | HSP90AA1RXFP1MGAMGAASI | |
| SCHEMBL26696761 | 0.76 | HSP90AA1 (0.48) | HSP90AA1RXFP1MGAMGAASI | |
| SCHEMBL22633155 | 0.76 | KEAP1 (0.56) | HSP90AA1MGAMGAASIMGAM2 | |
| SCHEMBL1519788 | 0.76 | MGAM (0.44) | HSP90AA1RXFP1MGAMGAASI | |
| SCHEMBL12410576 | 0.75 | HSP90AA1 (0.42) | HSP90AA1CYP2A6GAAMAPTMEN1 | |
| SCHEMBL12410587 | 0.74 | CYP2A6 (0.56) | CYP2A6HTTALDH1A1MTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3267996-B1 | PYRAZOLOPYRIMIDINE INHIBITORS OF IRAK4 ACTIVITY | MERCK SHARP & DOHME (US) | 2020-11-11 | — | — | EP | disclosed |
| US-20200055846-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2020-02-20 | — | — | US | disclosed |
| US-20200055846-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2020-02-20 | — | — | US | disclosed |
| US-10329294-B2 | Pyrazolopyrimidine inhibitors of IRAK4 activity | MERCK SHARP & DOHME CORP. (US) | 2019-06-25 | — | — | US | disclosed |
| US-10165775-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-10165775-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-20180051028-A1 | PYRAZOLOPYRIMIDINE INHIBITORS OF IRAK4 ACTIVITY | MERCK SHARP & DOHME CORP. (US) | 2018-02-22 | — | — | US | disclosed |
| EP-3267996-A1 | PYRAZOLOPYRIMIDINE INHIBITORS OF IRAK4 ACTIVITY | Merck Sharp & Dohme Corp. (US) | 2018-01-17 | — | — | EP | disclosed |
| US-20170267657-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-09-21 | — | — | US | disclosed |
| US-20170267657-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-09-21 | — | — | US | disclosed |
| WO-2012061290-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012061290-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | disclosed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | disclosed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | disclosed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | disclosed |
| US-20120095023-A1 | Novel Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20120095023-A1 | Novel Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20120095023-A1 | Novel Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| WO-2011128304-A2 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011128304-A2 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329294-B2 | Pyrazolopyrimidine inhibitors of IRAK4 activity | IRAK4, IRAK2, IRAK1 | HSP90AA1 2902/4885RXFP1 4235/4885CYP2A6 3594/4885 |
| US-20200055846-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | HSP90AA1 511/4885RXFP1 1210/4885CYP2A6 368/4885 |
| US-20120095023-A1 | Novel Heterocyclic Compounds as Pesticides | DDT, PTMS, AADAC | HSP90AA1 1075/4885RXFP1 3353/4885CYP2A6 1693/4885 |
| US-20170267657-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | HSP90AA1 511/4885RXFP1 1210/4885CYP2A6 368/4885 |
| US-20180051028-A1 | PYRAZOLOPYRIMIDINE INHIBITORS OF IRAK4 ACTIVITY | IRAK4, IRAK2, IRAK1 | HSP90AA1 2902/4885RXFP1 4235/4885CYP2A6 3594/4885 |
| US-10165775-B2 | Pesticidal compositions and processes related thereto | ACHE, DDT, PTMS | HSP90AA1 511/4885RXFP1 1210/4885CYP2A6 368/4885 |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | ACHE, DDT, PTMS | HSP90AA1 511/4885RXFP1 1210/4885CYP2A6 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.