SCHEMBL212150

SCHEMBL212150

O=Cc1cc(C23CC4CC(C2)CC(c2ccc(O)c(C=O)c2)(C4)C3)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
POLB P06746 1/20 0.53
GAA P10253 1/20 0.53
GFER P55789 1/20 0.53
ERN1 O75460 4/20 0.41
ALDH1A1 P00352 2/20 0.41
SPHK2 Q9NRA0 2/20 0.40
SPHK1 Q9NYA1 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
PGR P06401 3/20 0.38
ESR2 Q92731 1/20 0.38
LMNA P02545 1/20 0.38
ESR1 P03372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30089423 0.91 MEN1 (0.65) MEN1KMT2APOLBGAAGFER
SCHEMBL4080365 0.91 MEN1 (0.65) MEN1KMT2APOLBGAAGFER
SCHEMBL3970537 0.83 MEN1 (0.46) MEN1KMT2APOLBGAAGFER
SCHEMBL1972365 0.80 MEN1 (0.79) MEN1KMT2APOLBGAAGFER
SCHEMBL1237159 0.80 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL29485576 0.80 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL211920 0.79 ERN1 (0.39) MEN1KMT2APOLBGAAGFER
SCHEMBL4077106 0.78 MEN1 (0.65) MEN1KMT2APOLBGAAGFER
SCHEMBL3977955 0.78 MEN1 (0.59) MEN1KMT2APOLBGAAGFER
SCHEMBL3975212 0.76 MEN1 (0.57) MEN1KMT2APOLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7456323-B2 1,3-bis(3-formyl-4-hydroxyphenyl)adamantanes and polynuclear polyphenols derived therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-11-25 US claimed
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-02 US claimed
US-RE43067-E1 Method for producing new polynuclear poly(formylphenol) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-01-03 US disclosed
US-7750190-B2 reacting hexamethylene tetramine in presence of acid; industrial scale; photoresists HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-07-06 US disclosed
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-07-16 US disclosed
US-7456323-B2 1,3-bis(3-formyl-4-hydroxyphenyl)adamantanes and polynuclear polyphenols derived therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-11-25 US disclosed
US-7456323-B2 1,3-bis(3-formyl-4-hydroxyphenyl)adamantanes and polynuclear polyphenols derived therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-11-25 US disclosed
US-7456323-B2 1,3-bis(3-formyl-4-hydroxyphenyl)adamantanes and polynuclear polyphenols derived therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-11-25 US disclosed
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-02 US disclosed
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-02 US disclosed
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-02 US disclosed
JP-2007023019-A 1,3-BIS(3-FORMYL-4-HYDROXYPHENYL)ADAMANTANE AND POLYNUCLEAR POLYPHENOL DERIVED THEREFROM HONSHU CHEM IND CO LTD 2007-02-01 JP disclosed
WO-2006134909-A1 1,3-BIS(3-FORMYL-4-HYDROXYPHENYL)ADAMANTANES AND POLYNUCLEAR POLYPHENOLS DERIVED THEREFROM HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2006-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) PCBP1, FPR2, PNKP MEN1 3921/4885KMT2A 2272/4885POLB 88/4885
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HNMT, NEFM, CD69 MEN1 4682/4885KMT2A 2847/4885POLB 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.