SCHEMBL211920

SCHEMBL211920

Cc1cc(C23CC4CC(C2)CC(c2cc(C)c(O)c(C=O)c2)(C4)C3)cc(C=O)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.39
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
PGR P06401 3/20 0.34
ESR1 P03372 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD11B1 P28845 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
MDM2 Q00987 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12936012 0.90 ERN1 (0.44) ERN1MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL2048427 0.85 ACHE (0.43) MEN1KMT2APGRESR1SMN1; SMN2
SCHEMBL4955291 0.83 ESR1 (0.35) ERN1MEN1KMT2APGRESR1
SCHEMBL4954657 0.83 ERN1 (0.31) ERN1
SCHEMBL4955183 0.82 ERN1 (0.33) ERN1MEN1KMT2APGRESR1
SCHEMBL4954700 0.82 PTGS1 (0.33) ERN1MEN1KMT2APGRESR1
SCHEMBL4955197 0.80 PGR (0.33) ERN1MEN1KMT2APGRESR1
SCHEMBL212150 0.79 MEN1 (0.53) ERN1MEN1KMT2APGRESR1
SCHEMBL4954623 0.79 ESR1 (0.33) ERN1MEN1KMT2APGRESR1
SCHEMBL4949774 0.78 PGR (0.32) MEN1KMT2APGRESR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE43067-E1 Method for producing new polynuclear poly(formylphenol) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-01-03 US disclosed
US-7750190-B2 reacting hexamethylene tetramine in presence of acid; industrial scale; photoresists HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-07-06 US disclosed
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-07-16 US disclosed
US-7456323-B2 1,3-bis(3-formyl-4-hydroxyphenyl)adamantanes and polynuclear polyphenols derived therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-11-25 US disclosed
US-7456323-B2 1,3-bis(3-formyl-4-hydroxyphenyl)adamantanes and polynuclear polyphenols derived therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-11-25 US disclosed
US-7456323-B2 1,3-bis(3-formyl-4-hydroxyphenyl)adamantanes and polynuclear polyphenols derived therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-11-25 US disclosed
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-02 US disclosed
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-02 US disclosed
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) PCBP1, FPR2, PNKP ERN1 2895/4885MEN1 3921/4885KMT2A 2272/4885
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HNMT, NEFM, CD69 ERN1 3504/4885MEN1 4682/4885KMT2A 2847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.