Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11680913 | 0.83 | TSHR (0.53) | KDM4EL3MBTL1TSHRALDH1A1ATM | |
| SCHEMBL4521078 | 0.81 | ENPP2 (0.39) | ENPP2KDM4ETDP1MMP3TSHR | |
| SCHEMBL1466419 | 0.79 | RXRB (0.40) | ENPP2KDM4ETDP1MMP3TSHR | |
| SCHEMBL3452505 | 0.79 | NPC1 (0.46) | ENPP2KDM4ETDP1MMP3TSHR | |
| SCHEMBL29790934 | 0.78 | ENPP2 (0.37) | ENPP2KDM4ETDP1MMP3FFAR1 | |
| SCHEMBL27582186 | 0.78 | ENPP2 (0.37) | ENPP2KDM4ETDP1MMP3FFAR1 | |
| SCHEMBL2154504 | 0.72 | KMT2A (0.47) | ENPP2KDM4ETDP1MMP3L3MBTL1 | |
| SCHEMBL28840767 | 0.72 | PRMT5 (0.38) | ENPP2KDM4ETDP1MMP3TSHR | |
| SCHEMBL11528945 | 0.72 | TBXA2R (0.36) | ENPP2KDM4ETDP1MMP3L3MBTL1 | |
| SCHEMBL17656375 | 0.72 | ESR2 (0.37) | ENPP2KDM4ETDP1MMP3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019145726-A1 | COMPOUNDS | Enterprise Therapeutics Limited (GB) | 2019-08-01 | — | — | WO | disclosed |