Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21228700 | 0.90 | PTGES (0.44) | PTGESLMNAGAANPSR1TP53 | |
| SCHEMBL21220014 | 0.85 | LMNA (0.38) | LMNAGAATP53CYP1A2SMN1; SMN2 | |
| SCHEMBL21228630 | 0.85 | ABCB11 (0.34) | PTGESLMNAGAATP53SMN1; SMN2 | |
| SCHEMBL21225597 | 0.84 | PTGES (0.45) | PTGESLMNAGAANPSR1TP53 | |
| SCHEMBL21220024 | 0.81 | PTGES (0.51) | PTGESLMNAGAANPSR1TP53 | |
| SCHEMBL21220004 | 0.80 | NPC1 (0.43) | PTGESLMNAGAATP53TSHR | |
| SCHEMBL21220008 | 0.78 | ALDH1A1 (0.41) | LMNAGAATP53TSHRMAPK1 | |
| SCHEMBL21228671 | 0.76 | LMNA (0.36) | LMNAGAATP53TSHRMAPK1 | |
| SCHEMBL21228645 | 0.76 | TSHR (0.33) | PTGESLMNAGAATP53TSHR | |
| SCHEMBL12251014 | 0.75 | PTGES (0.55) | PTGESLMNAGAANPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927245-B2 | Non-migratory internal plasticizers attached to a pendant covalent linkage | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-23 | — | — | US | disclosed |
| US-10927245-B2 | Non-migratory internal plasticizers attached to a pendant covalent linkage | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-23 | — | — | US | disclosed |
| WO-2019152777-A2 | NON-MIGRATORY INTERNAL PLASTICIZERS ATTACHED TO A PENDANT COVALENT LINKAGE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-08-08 | — | — | WO | disclosed |
| US-20190241727-A1 | NON-MIGRATORY INTERNAL PLASTICIZERS ATTACHED TO A PENDANT COVALENT LINKAGE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-08-08 | — | — | US | disclosed |
| US-20190241727-A1 | NON-MIGRATORY INTERNAL PLASTICIZERS ATTACHED TO A PENDANT COVALENT LINKAGE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-08-08 | — | — | US | disclosed |