Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21228645 | 0.91 | TSHR (0.33) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL21220014 | 0.87 | LMNA (0.38) | TSHRLMNAMAPK1HCAR3ALDH1A1 | |
| SCHEMBL21228707 | 0.86 | ABCB11 (0.36) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL21220019 | 0.85 | — | — | |
| SCHEMBL21220009 | 0.85 | PTGES (0.46) | TSHRLMNAMAPK1PTGESALDH1A1 | |
| SCHEMBL21220004 | 0.82 | NPC1 (0.43) | TSHRLMNAMAPK1PTGESHCAR3 | |
| SCHEMBL21228671 | 0.79 | LMNA (0.36) | TSHRLMNAMAPK1HCAR3ALDH1A1 | |
| SCHEMBL21220008 | 0.77 | ALDH1A1 (0.41) | CYP3A4TSHRLMNAMAPK1HCAR3 | |
| SCHEMBL21228700 | 0.76 | PTGES (0.44) | TSHRLMNAMAPK1PTGESALDH1A1 | |
| SCHEMBL21220022 | 0.74 | LMNA (0.40) | CYP3A4TSHRLMNAMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927245-B2 | Non-migratory internal plasticizers attached to a pendant covalent linkage | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-23 | — | — | US | disclosed |
| US-20190241727-A1 | NON-MIGRATORY INTERNAL PLASTICIZERS ATTACHED TO A PENDANT COVALENT LINKAGE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-08-08 | — | — | US | disclosed |