Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 1.00 |
| ▸ | ACHE | P22303 | 8/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | APP | P05067 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.64 |
| ▸ | STAT3 | P40763 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.63 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2122038 | 1.00 | TRPV1 (1.00) | TRPV1ACHEKDM4EKMT2AMEN1 | |
| SCHEMBL2123701 | 0.91 | TRPV1 (0.87) | TRPV1ACHEKDM4EKMT2ACYP1A2 | |
| SCHEMBL5029885 | 0.91 | TRPV1 (0.87) | TRPV1ACHEKDM4EKMT2ACYP1A2 | |
| SCHEMBL2123698 | 0.91 | TRPV1 (0.87) | TRPV1ACHEKDM4EKMT2ACYP1A2 | |
| SCHEMBL9364141 | 0.90 | TRPV1 (0.81) | TRPV1ACHEKDM4EKMT2AMEN1 | |
| SCHEMBL9363901 | 0.90 | TRPV1 (0.81) | TRPV1ACHEKDM4EKMT2AMEN1 | |
| SCHEMBL17327997 | 0.88 | TRPV1 (0.97) | TRPV1ACHEKDM4EKMT2AHPGD | |
| SCHEMBL9029032 | 0.87 | TRPV1 (1.00) | TRPV1ACHEKDM4EKMT2AHPGD | |
| SCHEMBL9029039 | 0.87 | TRPV1 (1.00) | TRPV1ACHEKDM4EKMT2AHPGD | |
| SCHEMBL30887530 | 0.87 | TRPV1 (1.00) | TRPV1ACHEKDM4EKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722665-B2 | Cinnamido-pyrrolo[2,1-C][1,4]benzodiazepines as potential anticancer agents and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-05-13 | — | — | US | disclosed |
| US-20120095213-A1 | CINNAMIDO-PYRROLO[2,1-C][1,4]BENZODIAZEPINES AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETIES ACT (ACT XXI OF 1860)) (IN) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095213-A1 | CINNAMIDO-PYRROLO[2,1-C][1,4]BENZODIAZEPINES AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | GABRA1, GABRA4, GABRA5 | TRPV1 1460/4885ACHE 3971/4885KDM4E 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.