Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26759029 | 0.77 | HTR7 (0.56) | HTR7HTR1AHTR2ADRD2 | |
| SCHEMBL18641615 | 0.75 | HTR7 (0.46) | HTR7HTR1AHTR2ADRD2 | |
| Hydrochloric Acid SCHEMBL21229082 | 0.75 | HTR7 (0.54) | HTR7HTR1AHTR2ADRD2 | |
| SCHEMBL21229056 | 0.70 | NAMPT (0.38) | HDAC6MAPK1 | |
| SCHEMBL5653620 | 0.69 | SMN1; SMN2 (0.53) | DRD2HDAC6 | |
| SCHEMBL20659199 | 0.69 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL290401 | 0.69 | FPR2 (0.44) | HDAC6MAPK1 | |
| SCHEMBL21229126 | 0.69 | CHEK1 (0.43) | DRD2MAPK1 | |
| SCHEMBL21229078 | 0.68 | LSS (0.47) | — | |
| SCHEMBL23018439 | 0.68 | PDPK1 (0.37) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377748-B2 | Hepatitis B core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2019-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377748-B2 | Hepatitis B core protein modulators | HAVCR2, FABP1, MAVS | HTR7 3617/4885HTR1A 3143/4885HTR2A 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.