Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21250402 | 0.89 | KCNA3 (0.43) | L3MBTL1OGASMN1; SMN2HTTKMT2A | |
| SCHEMBL21229141 | 0.82 | PRKAB2 (0.42) | L3MBTL1OGASMN1; SMN2HTTKMT2A | |
| SCHEMBL18641566 | 0.81 | ALDH1A1 (0.37) | OGASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL18641445 | 0.78 | SMN1; SMN2 (0.43) | OGASMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL26759473 | 0.75 | CKS1B (0.47) | L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL18667338 | 0.75 | KCNA3 (0.45) | L3MBTL1OGASMN1; SMN2HTTKMT2A | |
| SCHEMBL18667340 | 0.75 | KCNA3 (0.41) | L3MBTL1KMT2A | |
| SCHEMBL18667341 | 0.74 | KCNA3 (0.45) | L3MBTL1OGASMN1; SMN2HTTKMT2A | |
| SCHEMBL21250399 | 0.72 | L3MBTL1 (0.36) | L3MBTL1SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL19984631 | 0.72 | DRD2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377748-B2 | Hepatitis B core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2019-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377748-B2 | Hepatitis B core protein modulators | HAVCR2, FABP1, MAVS | L3MBTL1 1920/4885OGA 975/4885SMN1; SMN2 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.