Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.59 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.59 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.59 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.59 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.59 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.59 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.59 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | YES1 | P07947 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | BMP4 | P12644 | 1/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.59 |
| ▸ | FLT1 | P17948 | 1/20 | 0.59 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.59 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12050716 | 0.82 | HRH3 (0.82) | LTA4HHRH3KCNH2HRH1 | |
| SCHEMBL18837471 | 0.80 | LTA4H (0.84) | LTA4HHRH3PTGS2PSMB1PSMB5 | |
| SCHEMBL25059331 | 0.78 | LTA4H (0.87) | LTA4HHRH3PTGS2PSMB1PSMB5 | |
| SCHEMBL21585115 | 0.78 | FLT1 (0.64) | LTA4HHRH3PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL22829521 | 0.75 | BMP4 (0.76) | LTA4HHRH3PRKAB2PRKAG1PRKAA2 | |
| Dorsomorphin SCHEMBL463155 | 0.74 | KDR (1.00) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL16965384 | 0.74 | KDR (0.56) | LTA4HHRH3PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL14970484 | 0.74 | LTA4H (0.97) | LTA4HHRH3KCNH2PSMB1PSMB5 | |
| Dorsomorphin SCHEMBL17845800 | 0.74 | KDR (0.98) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL7139563 | 0.73 | LTA4H (1.00) | LTA4HHRH3PSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521419-A1 | METHOD FOR PRODUCING SOMATIC CELL, SOMATIC CELL, AND COMPOSITION | Kyoto Prefectural Public University Corporation (JP) | 2019-08-07 | — | — | EP | disclosed |