Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25163584 | 0.80 | NOS3 (0.40) | LMNAPPARGPPARDPPARATRPV4 | |
| SCHEMBL20708127 | 0.77 | PPARG (0.46) | LMNAPPARGPPARDPPARATRPV4 | |
| SCHEMBL23507232 | 0.77 | LOXL2 (0.36) | PPARGPPARDPPARATRPV4LOXL2 | |
| SCHEMBL14183073 | 0.73 | NOS3 (0.44) | LMNAPPARDTRPV4LOXL2POLQ | |
| SCHEMBL14183066 | 0.73 | PDE10A (0.40) | TRPV4POLQCA2CHKAAAK1 | |
| SCHEMBL20465813 | 0.73 | NOS3 (0.52) | LMNAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL13696443 | 0.70 | NPSR1 (0.39) | PPARGPPARDPPARATRPA1CYP1A2 | |
| SCHEMBL16647331 | 0.70 | LMNA (0.42) | LMNARXRAGRIN1GRIN2BTRPA1 | |
| SCHEMBL26375194 | 0.70 | TRPV4 (0.39) | LMNATRPA1TRPV4LOXL2POLQ | |
| SCHEMBL16139569 | 0.70 | TRPV4 (0.39) | LMNACYP1A2TRPV4LOXL2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |