Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20708127 | 0.86 | PPARG (0.46) | LOXL2PPARGPPARDPPARALOX | |
| SCHEMBL25163584 | 0.81 | NOS3 (0.40) | LOXL2PPARGPPARDPPARALOX | |
| SCHEMBL21240967 | 0.77 | LMNA (0.38) | LOXL2PPARGPPARDPPARALOX | |
| SCHEMBL14183073 | 0.74 | NOS3 (0.44) | LOXL2PPARDLOXTRPV4CA2 | |
| SCHEMBL25848994 | 0.73 | LOXL2 (0.44) | LOXL2PPARGPPARDPPARALOX | |
| SCHEMBL26375194 | 0.71 | TRPV4 (0.39) | LOXL2LOXTRPV4CA2CHKA | |
| SCHEMBL19144982 | 0.71 | TRPV4 (0.39) | LOXL2LOXTRPV4CA2CHKA | |
| SCHEMBL16139569 | 0.71 | TRPV4 (0.39) | LOXL2TRPV4CA2CHKAHSP90AA1 | |
| SCHEMBL19146285 | 0.70 | NOS3 (0.53) | LOXL2PPARGPPARDPPARALOX | |
| SCHEMBL16389698 | 0.69 | TRPV4 (0.38) | LOXL2LOXTRPV4CA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438095-B1 | PYRIDAZINONE COMPOUND OR ITS SALT, AND HERBICIDE CONTAINING IT | ISHIHARA SANGYO KAISHA (JP) | 2021-06-16 | — | — | EP | disclosed |