Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952408 | 0.78 | AKT1 (0.38) | PIM1PIM3PIM2AKT1AKT2 | |
| SCHEMBL21233190 | 0.73 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2CHEK1 | |
| SCHEMBL21233334 | 0.72 | PIM1 (0.37) | PIM1LMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25753038 | 0.71 | BRD4 (0.39) | PIM1PIM3PIM2AKT1AKT2 | |
| SCHEMBL3740850 | 0.71 | AKT2 (0.70) | PIM1PIM3PIM2AKT1AKT2 | |
| SCHEMBL31028985 | 0.70 | KMT2A (0.52) | PIM1PIM3PIM2AKT1AKT2 | |
| SCHEMBL26934046 | 0.70 | HTR3A (0.42) | PIM1PIM3PIM2AKT1AKT2 | |
| SCHEMBL14996633 | 0.69 | SMN1; SMN2 (0.51) | LMNAALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL5280031 | 0.69 | RAB9A (0.51) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21233344 | 0.69 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |