Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18029231 | 0.81 | HTR6 (0.60) | CYP2A6HTR6HSD11B1PFKFB3MAPT | |
| SCHEMBL7528711 | 0.79 | HSD11B1 (0.47) | CYP2A6HTR6HSD11B1PFKFB3PIK3CB | |
| SCHEMBL30267989 | 0.78 | PFKFB3 (0.50) | CYP2A6HSD11B1PFKFB3PIK3CBPDE10A | |
| SCHEMBL30308690 | 0.74 | DYRK1A (0.65) | DYRK1ACLK1MAP4K4PIK3CBWNT3A | |
| SCHEMBL1896511 | 0.74 | DYRK1A (0.65) | DYRK1ACLK1MAP4K4PIK3CBWNT3A | |
| SCHEMBL18029140 | 0.74 | HSD11B1 (0.55) | CYP2A6HTR6HSD11B1 | |
| SCHEMBL7988012 | 0.73 | CYP2A6 (0.45) | CYP2A6HTR6HSD11B1PFKFB3PIK3CB | |
| SCHEMBL7527031 | 0.73 | HSD11B1 (0.42) | CYP2A6HSD11B1PFKFB3PIK3CBPDE10A | |
| SCHEMBL19903845 | 0.73 | HTR1D (0.59) | CYP2A6HTR6HSD11B1PDE10AMAPT | |
| SCHEMBL20660849 | 0.72 | ALDH1A1 (0.57) | DYRK1ACYP2A6HSD11B1PFKFB3PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |