Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241363 | 0.85 | ADORA2A (0.45) | ALDH1A1PTGS2ADORA2AADORA1PTGS1 | |
| SCHEMBL21241499 | 0.83 | LMNA (0.46) | ADORA2AADORA1GAAMAPTPTGS1 | |
| SCHEMBL21241365 | 0.83 | ADORA2A (0.43) | SDHBALDH1A1PTGS2CYP2C9ADORA2A | |
| SCHEMBL21241178 | 0.80 | PTGS2 (0.41) | PTGS2 | |
| SCHEMBL22598437 | 0.80 | KIF11 (0.45) | PDPK1CA12CA1CA2CA3 | |
| SCHEMBL21241087 | 0.79 | TRPA1 (0.41) | PTGS2PTGS1 | |
| SCHEMBL21241176 | 0.73 | ALOX5 (0.44) | PTGS2ADORA2AADORA1PTGS1CYP3A4 | |
| SCHEMBL17703505 | 0.72 | HSP90AA1 (0.35) | ALDH1A1GAALMNA | |
| SCHEMBL21241236 | 0.70 | MKNK1 (0.35) | PTGS2 | |
| SCHEMBL21241512 | 0.67 | ADORA2A (0.48) | SDHBALDH1A1ADORA2AADORA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |