Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PER2 | O15055 | 1/20 | 0.39 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046465 | 0.83 | POLB (0.44) | POLBLMNARECQLHTTGLA | |
| SCHEMBL14259041 | 0.77 | MAPT (0.47) | POLBLMNACA12CA2CA9 | |
| SCHEMBL13475062 | 0.77 | ACHE (0.48) | POLBLMNARECQLHTTGLA | |
| SCHEMBL11138993 | 0.77 | HTR7 (0.51) | POLBLMNAHTTTP53MAPT | |
| SCHEMBL11392000 | 0.76 | KMT2A (0.44) | POLBLMNARECQLTP53MAPT | |
| SCHEMBL9464711 | 0.76 | ALDH1A1 (0.51) | POLBLMNARECQLHTTGLA | |
| SCHEMBL9889004 | 0.75 | ACHE (0.46) | POLBHTTTP53ALDH1A1CYP3A4 | |
| SCHEMBL30659513 | 0.75 | ACHE (0.46) | POLBHTTTP53ALDH1A1CYP3A4 | |
| SCHEMBL11139614 | 0.73 | HTR7 (0.56) | TP53ALDH1A1KMT2AHTR7HSD17B1 | |
| SCHEMBL9446186 | 0.73 | SIGMAR1 (0.45) | LMNAHTTGLATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |