Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.67 |
| ▸ | KDM4A | O75164 | 1/20 | 0.67 |
| ▸ | KDM4B | O94953 | 1/20 | 0.67 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | WNT3A | P56704 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786433 | 0.86 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL4657817 | 0.85 | ADORA3 (0.72) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL21506003 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL21484682 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL2998083 | 0.83 | ADORA3 (0.79) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL21224224 | 0.82 | ELOVL1 (0.72) | ALDH1A1MAPTGAAADORA3LMNA | |
| SCHEMBL17716927 | 0.82 | ALDH1A1 (0.75) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL18997288 | 0.82 | ADORA3 (0.82) | ALDH1A1MAPTKDM4EPOLBGAA | |
| Hydrochloric Acid SCHEMBL21225294 | 0.81 | ELOVL1 (0.71) | ALDH1A1MAPTGAAADORA3LMNA | |
| SCHEMBL23714637 | 0.80 | KMT2A (0.48) | ALDH1A1MAPTKDM4EPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-04 | — | — | US | disclosed |
| US-20210038611-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2021-02-11 | — | — | US | disclosed |
| CN-112153984-A | Compound and use thereof | 福宏治疗公司 | 2020-12-29 | — | — | CN | disclosed |
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | ALDH1A1 2571/4885MAPT 2074/4885KDM4E 1848/4885 |
| US-20210038611-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | ALDH1A1 2571/4885MAPT 2074/4885KDM4E 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.