Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922120 | 1.00 | L3MBTL1 (0.54) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL21243068 | 0.83 | LMNA (0.62) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL8921545 | 0.77 | THRB (0.54) | KMT2AALDH1A1MAPTMEN1CYP1A2 | |
| SCHEMBL8920234 | 0.77 | THRB (0.54) | KMT2AALDH1A1MAPTMEN1CYP1A2 | |
| SCHEMBL8921547 | 0.77 | THRB (0.54) | KMT2AALDH1A1MAPTMEN1CYP1A2 | |
| Ethyl Nicotinate SCHEMBL8164637 | 0.76 | L3MBTL1 (0.71) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| Ethyl Nicotinate SCHEMBL24853 | 0.76 | L3MBTL1 (0.71) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| Ethyl Nicotinate SCHEMBL1330922 | 0.76 | L3MBTL1 (0.71) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| Ethyl Nicotinate SCHEMBL29958752 | 0.76 | L3MBTL1 (0.71) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL503334 | 0.75 | LMNA (0.59) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691366-A | UNSATURATED NITRO OXIME FORMED BY REACTION OF DINITROGEN TRIOXIDE WITH DIOLEFIN ETHER, SULFIDE OR AMINE TO BE USED AS VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5495023-A | VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0612315-A1 | NITRO COMPOUNDS HAVING VASODILATOR ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993010097-A1 | NITRO COMPOUNDS HAVING VASODILATOR ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-27 | — | — | WO | disclosed |