Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.47 |
| ▸ | HTR2B | P41595 | 5/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375462 | 0.85 | HTR2C (0.60) | HTR2CHTR2BSLC6A4HTR6 | |
| SCHEMBL12794525 | 0.81 | ADRB2 (0.48) | CSNK2A1PDE4BPDE4D | |
| SCHEMBL2909706 | 0.81 | PDE4A (0.51) | CSNK2A1SLC6A4PDE4BPDE4D | |
| SCHEMBL8296638 | 0.80 | ADRB2 (0.47) | CSNK2A1PDE4BPDE4D | |
| SCHEMBL24925307 | 0.79 | EIF4E (0.43) | CSNK2A1SLC6A4 | |
| SCHEMBL1047958 | 0.79 | ALDH1A1 (0.42) | CSNK2A1PDE4BPDE4D | |
| SCHEMBL29952216 | 0.78 | PDE4B (0.41) | HTR2CHTR2BCSNK2A1SLC6A4HTR6 | |
| SCHEMBL13722591 | 0.78 | PDE4B (0.41) | HTR2CHTR2BCSNK2A1SLC6A4HTR6 | |
| SCHEMBL23665255 | 0.78 | RBP4 (0.41) | HTR2CHTR2BCSNK2A1SLC6A4HTR6 | |
| SCHEMBL18768218 | 0.78 | RORC (0.46) | HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149965-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | UNIVERSITE DE STRASBOURG (FR) | 2019-08-08 | — | — | WO | disclosed |